The final Summit outcome document provided a renewed global endorsement of the Millennium Development Goals, and built on the major international agreements of recent years to consolidate a practical plan of action. Crucially, leaders agreed that every country would adopt and implement comprehensive national development strategies to achieve the internationally agreed development goals and objectives, including the Millennium Development Goals by 2006.

World leaders also agreed to adopt a number of "quick impact initiatives" in areas where rapid progress can be made, including the free distribution of malaria bed nets and effective anti-malarial treatments, the expansion of school meal programs using locally-produced foods, and the elimination of user fees for primary education. Leaders further agreed to launch an African Green Revolution and endorsed the operational goal of universal access to HIV/AIDS prevention, treatment services by 2010.